Antiphage effect of ethylenimines
| Autor: | L. B. Borisov |
|---|---|
| Rok vydání: | 1964 |
| Předmět: |
Ethylene
biology Biological macromolecule Biological activity General Medicine Buffer solution Ring (chemistry) biology.organism_classification Combinatorial chemistry General Biochemistry Genetics and Molecular Biology Bacteriophage chemistry.chemical_compound chemistry Molecule Organic chemistry Inhibitory effect |
| Zdroj: | Bulletin of Experimental Biology and Medicine. 57:325-327 |
| ISSN: | 1573-8221 0007-4888 |
| DOI: | 10.1007/bf00781919 |
| Popis: | Experimental data presented in this paper deal with the comparative study of the antiphage activity of ethylenimine and its mono- and polyderivatives. As established the degree of the inhibitory effect of the substances studied depended on their concentration, the pH of the buffer solution, the time of action upon the bacteriophage, and in some cases upon type of bacteriophage. In the authors opinion, different antiphage activity of ethylenimine derivatives is completely comparable with their different anti-tumour effect. High biological activity of such monofunctional ethylenimines, as ethoxen (1-ethylenimino-2-oxibutan-3) may be connected with the presence in its molecule of several reaction-capable groups, forming cross bonds in the biological macromolecule not only at the expense of ethylenimine ring, but also of the unsaturated ethylene or hydroxyl group. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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