Disposition of [14C]LY2606368 following intravenous administration in patients with advanced and/or metastatic solid tumours
Autor: | Kenneth C. Cassidy, Christopher D. Payne, Scott M. Hynes, Enaksha R Wickremsinhe, Yingying Guo |
---|---|
Rok vydání: | 2019 |
Předmět: |
Pharmacology
Intravenous dose medicine.medical_specialty business.industry Health Toxicology and Mutagenesis Oxidative deamination General Medicine Disposition Metabolism Toxicology 030226 pharmacology & pharmacy Biochemistry Gastroenterology Excretion 03 medical and health sciences 0302 clinical medicine 030220 oncology & carcinogenesis Internal medicine Medicine In patient business |
Zdroj: | Xenobiotica. 50:793-804 |
ISSN: | 1366-5928 0049-8254 |
Popis: | The disposition and metabolism of prexasertib, a CHK-1 inhibitor was characterised over a 120 h period following a single 170-mg intravenous dose of [14C]prexasertib (50 µCi) to 6 patients with adv... |
Databáze: | OpenAIRE |
Externí odkaz: |