Interactions of Ca, P, Zn and alkaline phosphatase in the chick—III. Effects of dietary phosphate, NaCl and theophylline

Autor: I. Motzok, L.W. McCuaig
Rok vydání: 1974
Předmět:
Zdroj: Comparative Biochemistry and Physiology Part A: Physiology. 48:663-674
ISSN: 0300-9629
DOI: 10.1016/0300-9629(74)90609-4
Popis: 1. 1. Low inorganic phosphate (Pi) diets, fed to chicks for 3 days, caused severe hypophosphataemia, while elevating plasma Ca and Zn levels. 2. 2. (Pi)-depletion also reduced duodenal mucosal (Pi), mucosal nuclear (Pi), mucosal alkaline phosphatase activity and increased the mucosal and nuclear Ca and Zn. 3. 3. Excess dietary NaCl enhanced bone mineralization, when dietary P was adequate, and tended to counteract the effects of (Pi)-deprivation. 4. 4. Theophylline reduced the growth, feed efficiency, plasma and mucosal nuclear (Pi), and tended to increase mucosal Ca and phosphatase. 5. 5. Mucosal phosphatase was positively correlated with plasma, mucosa and mucosal nuclear (Pi) levels and was inversely related to mucosa Zn levels. 6. 6. Duodenal alkaline phosphatase may regulate the metabolism of Ca and Zn via effects on the movements of (Pi).
Databáze: OpenAIRE