Development and Proof of Concept for a Large-Scale Photoredox Additive-Free Minisci Reaction

Autor: Zhang Enxuan, Chris D. Parsons, David C. McKinney, Kevin William Leslie, Zhi-qing Liu, Miguel Gonzalez, Mark A. Graham, Jackson Lucinda Victoria, Rachel H. Munday, Jun-wang Zhang, Janette H. Cherryman, James Douglas, David Whittaker, Gary M. Noonan
Rok vydání: 2020
Předmět:
Zdroj: Organic Process Research & Development. 25:57-67
ISSN: 1520-586X
1083-6160
DOI: 10.1021/acs.oprd.0c00483
Popis: New route development activities toward ceralasertib (AZD6738) have resulted in the discovery of an efficient, acid additive-free, photoredox Minisci reaction. Mechanistic understanding resulting f...
Databáze: OpenAIRE