A General Synthesis of 7-Phenyl-7,13-dihydro-8H-benzo[6,7]azepino[3,2-c]quinolin-8-ones

Autor:	Duyen H. T. Nguyen, Jeremy C. Dobrowolski, Benjamin H. Fraser, Naresh Kumar, Mohan M. Bhadbhade, David StC. Black
Rok vydání:	2019
Předmět:	010405 organic chemistry Organic Chemistry 010402 general chemistry Ring (chemistry) 01 natural sciences Combinatorial chemistry 0104 chemical sciences 3. Good health Umpolung chemistry.chemical_compound chemistry Rapid access Molecule Moiety Oxindole Azepine
Zdroj:	Synlett. 30:567-572
ISSN:	1437-2096 0936-5214
Popis:	Complex benzazepinoquinolone scaffolds can be accessed from the reaction of 2-aminoacetophenones and oxindole derivatives and feature the seven-membered azepine ring moiety commonly found in a range of drug molecules. The described reaction is generally applicable and allows for rapid access to a diverse range of new structures with further potential to build more elaborate molecules.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::086e22315bae3de0803470693dccd89b https://doi.org/10.1055/s-0037-1612106 Zobrazit plný text záznamu