Physiological effect of cholecystectomy on lipid profile of patients with cholelithiasis
| Autor: | Natasha Zahid, Naila Ikram, Hira Malik, Tahir Aslam, Shehzada Ameer Ahmed Babar, Anas Bin Tariq |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
medicine.diagnostic_test business.industry Cholesterol medicine.medical_treatment medicine.disease Gastroenterology chemistry.chemical_compound High-density lipoprotein chemistry Internal medicine Low-density lipoprotein medicine Pancreatitis Cholecystectomy Lipid lowering business Lipid profile Nephrotic syndrome |
| Zdroj: | International Journal of Scientific Reports. 6:243 |
| ISSN: | 2454-2164 2454-2156 |
| Popis: | Background: The association of cholecystectomy with alterations in lipid profile is well documented. Objectives of this study were to determine the effect of cholecystectomy on lipid profile of cholelithiasis patients.Methods: This cross-sectional observational study was done on 170 patients admitted in general surgery department of Naz Memorial Hospital, Karachi from July 2018 to June 2019. Symptomatic cholelithaisis patients between 18 to 60 years, elective cholecystectomy was included while patients previously on lipid lowering agents, diagnosed renal failure, nephrotic syndrome, cardiac failure, pregnant mothers, hypothyroidism, pancreatitis and obstructive jaundice were excluded. For data analysis, SPSS was used. Wilcoxon signed ranked test was used to compare mean values of pre and post-operative lipid profiles after cholecystectomy keeping p value of Results: 60% of patients were females with majority, 31% patients between 31-40 years while least, i.e. 11% were between 61-70 years. The mean pre-operative and post-operative difference of 52±7.32 mg/dl was seen in total cholesterol levels (pConclusions: Cholecystectomy in gall stone disease patients elicited favorable response in significantly lowering levels of total serum cholesterol, LDL and triglycerides while substantially increasing levels of HDL cholesterol. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|