Encapsulated Anaplastic Thyroid Carcinoma Transformed from Follicular Carcinoma
| Autor: | Alec Goldenberg, Michael Bannan, Aylin Simsir, Amy Rapkiewicz, Pascale Levine, Daniel F. Roses |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
medicine.medical_specialty
Pathology Histology medicine.diagnostic_test business.industry Cancer Anatomical pathology General Medicine medicine.disease Pathology and Forensic Medicine Thyroid carcinoma Fine-needle aspiration Poorly Differentiated Thyroid Carcinoma medicine Anaplastic carcinoma medicine.symptom business Anaplasia Thyroid cancer |
| Zdroj: | Acta Cytologica. 53:332-336 |
| ISSN: | 1938-2650 0001-5547 |
| DOI: | 10.1159/000325320 |
| Popis: | Background Anaplastic thyroid carcinoma (ATC) is rare but is one of the most aggressive and lethal human malignancies. Cytologically, ATC has a variable morphologic appearance, including squamoid, giant, spindled and pleomorphic cells. The coexistence of ATC and differentiated or poorly differentiated thyroid carcinoma has been described and usually is diagnosed when the disease is locally advanced. Case We describe a case of surgically resect-able, encapsulated, well-circumscribed ATC occurring in association with a better differentiated follicular carcinoma diagnosed by fine needle aspiration in a patient exposed to external ionizing radiation. Conclusion Encapsulated variants of anaplastic carcinoma can be seen in association with lower grade thyroid carcinoma such as follicular carcinoma. Accurate diagnosis is dependent on adequate sampling. |
| Databáze: | OpenAIRE |
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