Study of Nano-Mechanics of Collagen I Triple-helices by Computerized Processing of AFM Images

Autor:	Arkady Bitler, Sidney R. Cohen, Emanuel Perugia
Rok vydání:	2012
Předmět:	Persistence length Yield (engineering) Materials science Nano Scanning ion-conductance microscopy Nanomedicine Biomaterial Nanotechnology Mechanics Nanoscopic scale Triple helix
Zdroj:	MRS Proceedings. 1422
ISSN:	1946-4274 0272-9172
DOI:	10.1557/opl.2012.107
Popis:	We used atomic force microscope (AFM) to acquire high-resolution images of collagen type I triple-helices under ambient conditions in tapping mode. Angles between consecutive fixed-length segments were measured and analyzed to yield persistence length and elastic constant. Changing the segment length allowed exploring the mechanics at various scales. Understanding the mechanical properties of collagen molecules could serve to elucidate mechanisms of complex mechanical properties of interest in nanomedicine and nanotechnology.
Databáze:	OpenAIRE
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