Population-Based Cervical Screening with a 5-Year Interval in the Netherlands
| Autor: | Frederike C. Siemens, Mathilde E. Boon, Lambrecht P. Kok, Johan C. Kuypers |
|---|---|
| Rok vydání: | 2004 |
| Předmět: |
Gynecology
Cervical cancer education.field_of_study medicine.medical_specialty Histology Cervical screening Cost effectiveness business.industry Incidence (epidemiology) Population General Medicine Cervical intraepithelial neoplasia medicine.disease Pathology and Forensic Medicine Epidermoid carcinoma medicine education business Mass screening |
| Zdroj: | Acta Cytologica. 48:348-354 |
| ISSN: | 1938-2650 0001-5547 |
| DOI: | 10.1159/000326384 |
| Popis: | OBJECTIVE: To evaluate the outcome of population based cervical screening at 5-year intervals. STUDY DESIGN: Results from the west region of the Netherlands (population 2 million) were used. The 1995-2000 round was compared with the first 2 years of the second (2001-2002). All results were prospectively collected in a central database. Positive cytologies and histoscores per 1,000 screened for preinvasive squamous cervical intraepithelial neoplasia (CIN) lesions and invasive squamous cell carcinoma were calculated. RESULTS: In the first round, 378,081 women were screened; in the second round, 100,561 women were screened. In both rounds the youngest screenees had the highest cytoscores. Cytoscores in the first round did not differ significatly from those in the second. The histoscore for CIN 1 and 2 was 1.42 per 1,000 in the first round and 1.18 per 1,000 (NS, P CONCLUSION: Population-based screening at 5-year intervals in the Netherlands may result in stabilization of positive cytology and of the incidence of CIN and (histologic) invasive squamous cell carcinoma. The program seems more cost effective than that of 2 decades ago, with a screening interval of 3 years. |
| Databáze: | OpenAIRE |
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