Analysis of the Bacterial Vesicles' Enhanced Toxicological Threat Via Electron Microscopy

Autor: Lyubov V. Didenko, George A. Avtandilov, Roberta Curia, Francesco Tatti, Marziale Milani, Natalia V. Shevlyagina
Rok vydání: 2017
Předmět:
Popis: This study shows the importance of electron microscopy in the analysis of the interaction of microorganisms (Staphylococcus aureus) with polymeric (polyurethane) dental prostheses. Starting from the biofilm formation and the biodestruction of the plastic material resulting in the production of polyurethane nanoparticles, the focus is on the bacterial secretion of membrane vesicles (in the range of 20-50 nm) loaded with plastic nanoparticles (from 2-3 to 10 nm) and on the toxicological threat that these delivery devices represent when interacting with host cells. The nanoparticles deliverance led by the bacterial infections dynamics opens new ways to the possibility of delivering drugs to selected cells.
Databáze: OpenAIRE