The reactivity of the hydrofluorocarbon 1,1,1,2-tetrafluoroethane (HFC-134a) and related compounds towards base attack. The generation and stability of the tetrafluoroethyl, trifluorovinyl and related anions
Autor: | I. B. Haslock, James Burdon, Paul L. Coe, Richard L. Powell |
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Rok vydání: | 1999 |
Předmět: |
Solvent system
chemistry.chemical_classification Base (chemistry) Stereochemistry Organic Chemistry Ether Biochemistry Medicinal chemistry 1 1 1 2-Tetrafluoroethane Inorganic Chemistry chemistry.chemical_compound chemistry Environmental Chemistry Reactivity (chemistry) Hydrofluorocarbon Physical and Theoretical Chemistry Difluoromethane 1 1 1-Trifluoroethane |
Zdroj: | Journal of Fluorine Chemistry. 99:127-131 |
ISSN: | 0022-1139 |
DOI: | 10.1016/s0022-1139(99)00182-7 |
Popis: | Trifluorovinyllithium (CF2 = CFLi) has been successfully synthesised from 1,1,1,2-tetrafluoroethane using n-butyllithium at −78°C in ether. Other bases (LDA, DBU, MeLi, t-BuLi, t-BuOK) were tried with varied success. The stability of the system was dependent on temperature, concentration and solvent system employed. 1-Chloro-2,2,2-trifluoroethane (133a) led to an analogous polyfluorovinyllithium, but 1,1,1-trifluoro- and 1,1,1,2,2,2-hexafluoro- ethane did not. |
Databáze: | OpenAIRE |
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