VgrG Spike Dictates PAAR Requirement for the Assembly of the Type VI Secretion System

Autor: Xiaoye Liang, Hao-Yu Zheng, Ya-Jie Zhao, Yi-Qiu Zhang, Tong-Tong Pei, Yang Cui, Ming-Xuan Tang, Ping Xu, Tao Dong
Rok vydání: 2023
Předmět:
Zdroj: Journal of Bacteriology. 205
ISSN: 1098-5530
0021-9193
DOI: 10.1128/jb.00356-22
Popis: Gram-negative bacteria often encode multiple paralogs of the cone-shaped PAAR that sits atop the VgrG-spike and is thought to sharpen the spear-like T6SS puncturing device. However, it is unclear why PAAR is required for the assembly of some but not all T6SSs and why there are multiple PAARs if they are not required.
Databáze: OpenAIRE