Prevalence of pancreatic, hepatic and renal microscopic lesions in post-mortem samples from cavalier King Charles spaniels
| Autor: | Andrew Kent, Penelope Watson, Fernando Constantino-Casas, Brendan Corcoran, Margaret Carter, Tania Ledger, Clare Rusbridge |
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| Rok vydání: | 2016 |
| Předmět: |
Cavalier King Charles spaniel
medicine.medical_specialty education.field_of_study Pathology biology 040301 veterinary sciences business.industry biology.animal_breed Population 0402 animal and dairy science 04 agricultural and veterinary sciences Disease medicine.disease 040201 dairy & animal science 0403 veterinary science Severity of illness Medicine Pancreatitis Histopathology Clinical significance Small Animals business education Liver pathology |
| Zdroj: | Journal of Small Animal Practice. 57:188-193 |
| ISSN: | 0022-4510 |
| Popis: | OBJECTIVES The objective of this study was to describe the prevalence of microscopic pancreatic, hepatic and renal lesions in post-mortem samples from cavalier King Charles spaniels. METHODS The prevalence of microscopic lesions was determined by routine histopathology and compared to ante-mortem clinical signs. RESULTS There was evidence of chronic pancreatitis in 51·9% of the cases, and age correlated with severity. Renal lesions were diagnosed in 52·2% of cases, most of which were inflammatory. Ante-mortem diagnosis of pancreatic and renal disease was 25 and 16·7%, respectively. Primary hepatic lesions were diagnosed in 11·1% of cases; secondary hepatic lesions were diagnosed in 64·8%. CLINICAL SIGNIFICANCE Pancreatic and renal lesions are common in cavalier King Charles spaniels, but they have similar rates of hepatic disease as the general population. The increasing prevalence of pancreatic lesions with age suggests that it might be a progressive condition. |
| Databáze: | OpenAIRE |
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