A linear code parameter search algorithm with applications to immunology

Autor:	Gregory M. Constantine, Yoram Vodovotz, Carson C. Chow, John Bartels, Gilles Clermont
Rok vydání:	2007
Předmět:	Mathematical optimization Control and Optimization Applied Mathematics Exponential integrator Linear code Integrating factor Computational Mathematics Nonlinear system Linear differential equation Distributed parameter system Search algorithm Algorithm Differential algebraic equation Mathematics
Zdroj:	Computational Optimization and Applications. 42:155-171
ISSN:	1573-2894 0926-6003
Popis:	The immune system is modeled by way of a system of ordinary differential equations involving a large number of parameters, such as growth rates and initial conditions. Key to successful implementation of the model is the estimation of such parameters from available data. A parameter search algorithm based on linear codes is developed having as aim the identification of different regimes of behaviour of the model, the estimation of parameters in a high dimensional space, and the model calibration to data.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::083107cca57e60a6a72884a1505865c2 https://doi.org/10.1007/s10589-007-9118-9 Zobrazit plný text záznamu Full text from SpringerLink