Different electrochemical behavior of adult and fetal hemoglobin at ionic liquid-carbon nanotube nanocomposite

Autor:	Aghdas Banaei, Hedayatollah Ghourchian, Rezan Amjadi, Ali Akbar Moosavi Movahedi, Parvaneh Rahimi
Rok vydání:	2014
Předmět:	chemistry.chemical_compound Nanocomposite chemistry Ionic liquid Inorganic chemistry Fetal hemoglobin General Chemistry Hemoglobin Electrochemistry Hydrogen peroxide Heme Redox
Zdroj:	Journal of the Iranian Chemical Society. 12:687-694
ISSN:	1735-2428 1735-207X
Popis:	The direct electrochemistry of human adult and fetal hemoglobin on the surface of nanocomposite containing the carboxylated multi-walled carbon nanotubes (MWCNTs) and a hydrophilic room temperature ionic liquid (RTIL) has been reported. The voltammetric results showed that both types of hemoglobins entrapped in RTIL-MWCNTs nanocomposite displayed a pair of well defined, quasi-reversible redox peaks, corresponding to the Fe(III)/Fe(II) redox couple of heme prosthetic group, with the formal potentials of −0.234 and −0.232 V (vs. Ag/AgCl) for human adult and fetal hemoglobin, respectively. Immobilized human fetal hemoglobin on RTIL-MWCNTs nanocomposite relative to immobilized human adult hemoglobin showed slight differences in reversibility, electron transfer rate and protein-substrate affinity toward hydrogen peroxide.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::081730057bade2f2da55e820a90b50dd https://doi.org/10.1007/s13738-014-0527-2 Zobrazit plný text záznamu Full text from SpringerLink