A selective reaction that can be used to attach moenomycin to solid supports and proteins

Autor:	Lothar Hennig, Uwe Kempin, Astrid Markus, Dietrich Müller, Peter Welzel
Rok vydání:	1996
Předmět:	Selective reaction Moenomycin A Chemistry Stereochemistry Organic Chemistry Drug Discovery medicine Biochemistry Combinatorial chemistry Chloride medicine.drug
Zdroj:	Tetrahedron Letters. 37:5087-5090
ISSN:	0040-4039
DOI:	10.1016/0040-4039(96)01035-0
Popis:	A selective reaction at unit A of the antibiotic moenomycin A ( 1 ) has been developed: Reaction of 1 with o -nitrobenzenediazonium chloride cleanly yielded 12 . This compound is as active as moenomycin against Staph. aureus SG 511 and as an in-vitro transglycosylase inhibitor.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::07f588eb0d5376df29273490c3eff3f9 https://doi.org/10.1016/0040-4039(96)01035-0 Zobrazit plný text záznamu Full Text from ScienceDirect