Abstract 10165: The Correlation of Age and Extension Length in Debakey Type I Aortic Dissection: Are Septuagenarians at a Lower Risk?
| Autor: | Julia Merkle-Storms, Thorsten Wahlers, Manuel Feisst, Jochen Poeling, Bartosz Rylski, Daniel S Dohle, Christian Hagl, Tobias Krueger, Jens Brickwedel, Tomas Holubec, Christian D Etz, Thilo Noack, RAWA ARIF, Andreas Boening, Maximilian Luehr |
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| Rok vydání: | 2021 |
| Předmět: | |
| Zdroj: | Circulation. 144 |
| ISSN: | 1524-4539 0009-7322 |
| DOI: | 10.1161/circ.144.suppl_1.10165 |
| Popis: | Introduction: Elderly patients have been suggested to be more prone to acute aortic dissection due to a higher incidence of age-related atherosclerosis and stiffness of the thoracic aorta. Hypothesis: Younger patients suffer more extensive DeBakey type I dissections due to aortic wall integrity, potentially allowing unhindered extension. The study's aim was to correlate age and dissection extension length in a large contemporary multi-center cohort. Methods: The perioperative data of 3385 patients with acute aortic dissection were retrospectively analyzed with regard to postoperative outcome and dissection extent. DeBakey type I aortic dissections (n=2510) were identified and divided into two groups: 70 years (n=769). Patients with DeBakey type II and connective tissue disease were excluded (n=875). Results: Septuagenarians (>70 yrs) had a higher incidence of atherosclerosis (32.0% vs. 18.9%; pFig.1 ). Clinically, younger patients presented with significantly higher incidences of preoperative cerebral (p=0.002), spinal (p=0.003), visceral (p=0.002) and peripheral (p70 yrs were 18.9% and 22.2% (p=0.067), respectively. Conclusions: Extensive DeBakey type I aortic dissection is less frequent in septuagenarians. Conversely, younger patients suffer significantly more often from preoperative organ malperfusion and associated complications. Postoperative mortality remains high irrespective of age groups. |
| Databáze: | OpenAIRE |
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