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The use of Radiation Therapy (RT) in lung cancer has shown some exciting and sometimes disappointing advances in recent years. Protons compared with photons interact differently with human tissues, and can be used to improve patient care suffering lung cancer. A new strategy is the simultaneous injection of Nanoparticles (NPs) with proton radiation to the tumor which has been given over a decade to improve conventional RT. In this work, Proton Beam Therapy (PBT) with Gold Nanoparticles (GNPs) is used as part of a combination program for the treatment of advanced localized lung cancers. The purpose of this paper is developing the complex GEANT4 (G4) model on the human lung and predict the distribution of absorbed dose in lung tumors during proton therapy without and with high-Z injection of GNPs. Thus, the distribution of the absorbed dose in lung tumor for four modes of Bethe-Bloch’s relativistic quantum theory, G4 simulation model, hartree-fock-roothaan wave functions and the bortfeld theoretical model without and with the injection of GNPs in predicted phantom of the lung are compared. |
