Models of Cadmium Accumulation and Toxicity toHyalella aztecaduring 7- and 28-Day Exposures

Autor:	Uwe Borgmann, Lisa A. Golding, D.G. Dixon, J. E. Schroeder
Rok vydání:	2010
Předmět:	Cadmium biology Health Toxicology and Mutagenesis Ecological Modeling Hyalella azteca Biotic Ligand Model chemistry.chemical_element biology.organism_classification Pollution Acclimatization Acute toxicity Azteca chemistry Environmental chemistry Bioaccumulation Toxicity
Zdroj:	Human and Ecological Risk Assessment: An International Journal. 16:560-587
ISSN:	1549-7860 1080-7039
DOI:	10.1080/10807031003788808
Popis:	The inhibition of Cd accumulation by Ca in the amphipod Hyalella azteca in short-term (7-d) exposures appears to follow anti-competitive, rather than competitive, inhibition. Increasing Ca reduces Cd accumulation more at high than at low Cd concentrations. Cadmium accumulation and toxicity in chronic exposures can be predicted using the 7-d model to which the effects of acclimation, Cd inhibition of acclimation, and growth dilution are added. The resultant model is complex and species-specific, making it unwieldy for direct application in water quality guideline or criteria development. However, it does demonstrate that a mechanistic explanation of the relationship between short- and long-term accumulation and toxicity is possible, as well as suggest why the acute-to-chronic ratio changes with water chemistry. It is not, therefore, appropriate to estimate chronic Cd toxicity to H. azteca from acute toxicity assuming a constant acute-to-chronic ratio. The standard Biotic Ligand Model (BLM) can als...
Databáze:	OpenAIRE
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