Cytoskeletal Fluidization and Resolidification are Required for Reorientation of Endothelial Cells

Autor: James P. Butler, Jeffrey J. Fredberg, Dimitrije Stamenović, Ramaswamy Krishnan, Kavitha Rajendran, Greeshma Manomohan, Michael L. Smith, Athanassios P. Pirentis, Andreea L. Iordan, Elizabeth P. Canović
Rok vydání: 2012
Předmět:
Zdroj: ASME 2012 Summer Bioengineering Conference, Parts A and B.
Popis: Vascular endothelial cells are subjected to routine mechanical stretch. In response, cellular microstructures rearrange locally as the cell body realigns globally [1–5]. These responses, which underlie the vital functions of the endothelium, are often explained in terms of upstream mechanosensing and downstream cell signaling [2–5].Copyright © 2012 by ASME
Databáze: OpenAIRE