Bedside assessment of fibrinogen level in postpartum haemorrhage by thrombelastometry

Autor:	René-Charles Rudigoz, C Huissoud, Massignon D, A. Levrat, N. Carrabin, Michel Berland, François Audibert
Rok vydání:	2009
Předmět:	education.field_of_study Pregnancy business.industry Abnormal bleeding Population Obstetrics and Gynecology medicine.disease Fibrinogen Postpartum haemorrhage Clotting time Hemostasis Anesthesia medicine education Prospective cohort study business medicine.drug
Zdroj:	BJOG: An International Journal of Obstetrics & Gynaecology. 116:1097-1102
ISSN:	1470-0328
DOI:	10.1111/j.1471-0528.2009.02187.x
Popis:	Objectives To establish whether reagent-supported thrombelastometry with the rotation thrombelastometry system (ROTEM®) point-of-care device correlated with fibrinogen level in postpartum haemorrhages. Design Prospective observational study. Population and setting Ninety-one women at the third trimester of pregnancy: 37 with postpartum haemorrhage (study group) and 54 without abnormal bleeding (control group). Methods Standard laboratory test results were compared with those obtained at bedside from the ROTEM with the FIBTEM® test (54 tests in the control group and 51 in the study group). Main outcome measures Analysis of correlations between fibrinogen levels and FIBTEM test results: clotting time (CT), clot amplitude at 5 and 15 minutes (CA5; CA15) and maximal amplitude [maximum clot firmness (MCF)]. Results Median fibrinogen level was significantly lower in the haemorrhage group than in the control group (3.4 and 5.1 g/l, respectively, P
Databáze:	OpenAIRE
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