Hepatitis-B-Marker-Inzidenz in der Schwangerschaft: Vergleich mit den gesetzlich vorgeschriebenen serologischen Untersuchungen im Rahmen der Mutterschaftsvorsorge

Autor: E Haubold, P Mariss
Rok vydání: 2008
Předmět:
Zdroj: DMW - Deutsche Medizinische Wochenschrift. 111:1757-1760
ISSN: 1439-4413
0012-0472
DOI: 10.1055/s-2008-1068705
Popis: In a prospective study (June 1981 to October 1985) the prevalence of positive hepatitis B findings was recorded for 15957 pregnant women, in addition to the usual legally required serological tests for syphilis, newborn haemolytic disease and rubella immunity. A positive TPHA test was obtained in 69 (0.4%). No rubella antibodies were detected in 1604 (10.1%). Antibodies to neonatal haemolytic disease were found in 65 pregnant women (0.4%) and HBs antigen in 180 (1.1%). Among 13,752 German pregnant women 81 were HBs antigen-positive (0.6%), among 763 pregnant women from southern Europe 29 (3.8%), among 1159 from the Near East the rate was 5.1%, and among 170 from the Far East or other non-European countries it was 6.5%. By extending the required tests during pregnancy to those for HBs antigen, hepatitis B carriers could be identified and maternofetal transmission of the disease prevented by simultaneous passive-active immunization of the newborn.
Databáze: OpenAIRE