| Popis: |
Our purpose in the present report is to describe observations on the effects of postural changes and angiotonin injections on arterial pressure, pulse rate and renal hemodynamics in a patient who suffered from orthostatic hypotension and who was effectively treated by the head-up bed described by MacLean and Allen.1Briefly stated, before treatment the patient responded to a tilt of 60 degrees by syncope, decreased arterial pressure and renal blood flow. Injection of angiotonin greatly increased the blood pressure and renal blood flow. This effect of angiotonin contrasts sharply with the renal ischemia which accompanies its pressor action in normotensive subjects. After two months' treatment with the head-up bed a tilt to 60 degrees did not cause syncope, and renal blood flow was increased in spite of a transient decrease of arterial pressure. The injection of angiotonin at this time resulted in its characteristic pressor and renal vasoconstrictor effects. |
