Intradural Extramedullary Tumor Causing Compression of the Thoracic and Lumbar Vertebrae in a 22-year-old Male with Acute Myeloid Leukemia

Autor:	Joven Jeremius Q. Tanchuco, Ronna Cheska V. De Leon, Ma. Angelina L. Mirasol, Camille Ariadne C. Tanchanco
Rok vydání:	2020
Předmět:	Pathology medicine.medical_specialty business.industry Myeloid leukemia General Medicine Lumbar vertebrae medicine.disease Spinal cord Leukemia Myelogenous medicine.anatomical_structure Spinal cord compression hemic and lymphatic diseases medicine Myeloid sarcoma Paraplegia business
Zdroj:	Acta Medica Philippina. 54
ISSN:	2094-9278 0001-6071
DOI:	10.47895/amp.v54i2.1528
Popis:	Myeloid sarcoma, characterized by the presence of immature myeloid cells occurring at an extramedullary site, is a rare manifestation of acute myelogenous leukemia (AML). Spinal cord compression as an initial presentation of AML is very rare with only a few reported cases. We discuss a case of a 22-year-old male who presented with bicytopenia and paraplegia. Workups were consistent with AML with monocytic differentiation. Chromosomal analysis revealed loss of Y and t (8;21). Spinal cord MRI showed intradural extramedullary-enhancing soft tissue lesions at levels T2 to T7 and L5 to S1, suspected to be myeloid sarcoma. Patient, however, succumbed to severe nosocomial infection prior to initiation of chemotherapy and radiotherapy.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::078435d9c46b1bf0bd9a18be06c3cd28 https://doi.org/10.47895/amp.v54i2.1528 Zobrazit plný text záznamu