Revisión de la diana para la estimulación cerebral profunda de la cefalea en racimos crónica

Autor: Antonio Saiz-Ayala, Fernando Fernández-González, Elisa Seijo-Zazo, Javier Sol, Marco Antonio Alvarez-Vega, Beatriz Lozano-Aragoneses, Elena Santamarta-Liébana, Fernando Seijo-Fernandez
Rok vydání: 2011
Předmět:
Zdroj: Revista de Neurología. 52:366
ISSN: 0210-0010
Popis: Cluster headache is included in the group of trigeminal autonomic cephalalgias. Although the pathophysiology of cluster headache has not yet been sufficiently established, the theory of a central origin tells us that this headache is produced by hypothalamic dysfunction. More than 50 patients have been treated with deep brain stimulation of the posterior nucleus of the hypothalamus from 2001. The results show clinical improvement in more than 60% of the cases, opening a promising issue for the treatment of the cluster headache persistent after medical treatment. The surgical target that have been used until now is based on the origin of the cluster headache in the hypothalamic dysfunction. Nevertheless, It has still some open questions as the lack of proving the posterior nucleus of the hypothalamus is the real origin of the cluster headache, the lack of consensus about the anatomy of the surgical target and the variability of the structures stimulated with the surgery. The aim of this article is a review of the target used and propose another surgical target based on physiopathological concepts to explain the improvement with the deep brain stimulation in these patients.
Databáze: OpenAIRE