ChemInform Abstract: Total Synthesis of Balanol: A Potent Protein Kinase C Inhibitor of Fungal Origin

Autor:	I. Warner, Michael B. Hursthouse, Nigel Vicker, D. E. Hibbs, C. J. Hardy, S. M. Fairway, Andrew David Morley, B. W. Sharp, C. P. Adams
Rok vydání:	2010
Předmět:	chemistry.chemical_compound Fungal metabolite chemistry Biochemistry Total synthesis General Medicine Protein kinase A Ring (chemistry) Protein kinase C Balanol
Zdroj:	ChemInform. 27
ISSN:	0931-7597
Popis:	The total synthesis of the fungal metabolite balanol, a potent inhibitor of protein kinase C, is described. The synthesis includes a novel synthesis of 3-amino-4-hydroxyazepanes via a directed ring expansion of 3-bromopiperidin-4-ones.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::0774a06a93f68b0bcf5f35832cc099ee https://doi.org/10.1002/chin.199603259 Zobrazit plný text záznamu Plný text