ChemInform Abstract: Total Synthesis of Balanol: A Potent Protein Kinase C Inhibitor of Fungal Origin
Autor: | I. Warner, Michael B. Hursthouse, Nigel Vicker, D. E. Hibbs, C. J. Hardy, S. M. Fairway, Andrew David Morley, B. W. Sharp, C. P. Adams |
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Rok vydání: | 2010 |
Předmět: | |
Zdroj: | ChemInform. 27 |
ISSN: | 0931-7597 |
Popis: | The total synthesis of the fungal metabolite balanol, a potent inhibitor of protein kinase C, is described. The synthesis includes a novel synthesis of 3-amino-4-hydroxyazepanes via a directed ring expansion of 3-bromopiperidin-4-ones. |
Databáze: | OpenAIRE |
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