Sporadic coronavirus lower respiratory tract infection in adults: chest CT imaging features and comparison with other viruses
| Autor: | Madeline A. Danny, Lawrence A. Marinari, Wallace T. Miller |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Pathology
medicine.medical_specialty biology business.industry viruses Chest ct virus diseases Acute infection Pulmonary disease respiratory system medicine.disease_cause medicine.disease biology.organism_classification Virus respiratory tract diseases Human metapneumovirus Lower respiratory tract infection medicine Respiratory system business Coronavirus |
| Zdroj: | Respiratory infections. |
| DOI: | 10.1183/13993003.congress-2019.pa4547 |
| Popis: | Coronavirus(CoV) has been associated with lower respiratory tract infection(LRTI) in adults worldwide. The CoV associated with Sudden Acute Respiratory Syndrone and Middle East Respiratory Syndrone typically cause ground-glass opacities(GGO) and/or consolidation on chest CT. Chest CT features of sporadic CoV(subtypes: HKU1, NL63, OC43, 229E) have not been characterizedc. Our aims were to characterize chest CT features of sporadic CoV and compare these findings with those from other viruses. We retrospectively reviewed the records and chest CT images of 61 adults over 32 months at 4 community hospitals in the northeast US. CT images were reviewed by an experienced thoracic radiologist. Study subjects satisfied 4 criteria: 1) symptoms of acute LRTI, 2) positive polymerase chain reaction assay for CoV, 3)CT within 7 days of positive assay for CoV, 4)no other pulmonary infection or other pulmonary disease that might interfere with CT interpretation. We compared the chest CT features of sporadic CoV with those we previously reported for adenovirus, influenza, human metapneumovirus (hMPV), parainfluenza virus (PIV) and respiratory syncytial virus. On review of CoV cases, 11(18%) had bronchial wall thickening, 15(25%) had GGO, 12(20%) had lung consolidation and 13(21%) had tree-in-bud opacities. Twenty-eight(46%) had no chest CT findings related to acute infection. Sporadic CoV was similar to influenza but different from PIV (p |
| Databáze: | OpenAIRE |
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