Protection of Thiols

Autor: V. R. Rao, R. G. Hiskey, W. G. Rhodes
Rok vydání: 1973
Předmět:
Zdroj: Protective Groups in Organic Chemistry ISBN: 9781468472202
Popis: The presence of cysteine and cystine residues in many polypeptides of natural origin and the importance of these residues as either components of an ‘active site’ or in the stabilization of the native conformation of the molecule has closely aligned the development and use of sulphur protective groups with the chemical synthesis of polypeptides. This chapter will therefore deal primarily with the protection of cysteine residues and the means by which cysteine residues may be deblocked and converted to cystine or retained as the thiol.
Databáze: OpenAIRE