Microbial-chemical routes to R and S-denopamine a useful drug for congestive heart failure

Autor:	Guo-Qiang Lin, Zu-Yi Li, Jian‐Xin Gu
Rok vydání:	2010
Předmět:	Drug chemistry.chemical_classification Ketone Stereochemistry media_common.quotation_subject Denopamine General Chemistry Geotrichum sp medicine.disease chemistry.chemical_compound chemistry Heart failure medicine Organic chemistry Enantiomer media_common
Zdroj:	Chinese Journal of Chemistry. 13:475-480
ISSN:	1001-604X
DOI:	10.1002/cjoc.19950130516
Popis:	Both enantiomers of denopamine were synthesized using microbial-chemical approach via bioreduction of 1-(acetoxyphenyl)ketone 4(RCH2Cl) and 5(RCO2Et) with fungus Geotrichum sp. G38.
Databáze:	OpenAIRE
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