Escherichia coli bacteremia: Clinical features, risk factors and clinical implication of antimicrobial resistance

Autor: Fawzia E. Al-Otaibi, Elham E. Bukhari
Rok vydání: 2017
Předmět:
Zdroj: African Journal of Microbiology Research. 11:38-44
ISSN: 1996-0808
DOI: 10.5897/ajmr2016.8381
Popis: Escherichia coli is an important cause of both community acquired (CA) and hospital acquired (HA) bacteremia. A prospective study was conducted at a tertiary care University Hospital from January, 2012 to July 2014, to compare the clinical features, risk factors, outcomes and antimicrobial resistance between E. coli bacteremia acquired from the community (CA) versus E. coli bacteremia acquired from the hospital (HA). Clinical and laboratory data of 171 adult patients with at least one positive blood culture of E. coli were analyzed. Data were collected from patients with significant blood stream infection, using medical and laboratory record files and information from treating medical staff. The overall incidence of extended spectrum beta lactamase (ESBL) infection was high, 67/171 (77.4%). Thirty-eight (40.9%) of the CA isolates were found to produce ESBL, while 28 (35.9%) of the HA isolates were ESBL producers. Patients with CA bacteremia tend to be older than those with HA bacteremia (0.003). Neoplastic diseases (hematological malignancy (
Databáze: OpenAIRE