ChemInform Abstract: Synthesis of Geminal Bis- and Tristriazoles: Exploration of Unconventional Azide Chemistry

Autor:	Hellmuth Erhardt, Fabian Mohr, Stefan F. Kirsch
Rok vydání:	2016
Předmět:	chemistry.chemical_classification chemistry.chemical_compound Geminal chemistry Triazole derivatives Alkyne General Medicine Azide Combinatorial chemistry
Zdroj:	ChemInform. 47
ISSN:	0931-7597
Popis:	A range of geminal bis- and tristriazoles are presented. These rare and hardly studied compound classes were easily synthesized using ethyl 2,2-diazido-3-oxobutanoate as the common starting point. Firstly, CuAAC-reaction with an alkyne afforded the corresponding deacetylated bistriazoles. Upon further azidation yielding azidomethylenebistriazoles, a second CuAAC-functionalization then led to the creation of the geminal tristriazole compounds.
Databáze:	OpenAIRE
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