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Introduction: The report of doctors who died with COVID-19 in Indonesia was high and influenced by several factors. This study examined COVID-19 infected doctors and mortality risk factors in East Java. Material and Methods: This observational cohort study was conducted among doctors infected with COVID-19 in East Java during March 2020-September 2021 and collected the COVID-19 infected doctors’ deaths report. Doctors received a questionnaire on the status of COVID-19, history of covid-19 infection, age, sex, type of doctor, type of specialization and resident, pregnancy, underlying disease and nutritional status. All data were described and potential risk factors’ association was analyzed. Results: We reported 2041 doctors infected with COVID-19. Majority of them (52,5%) was male, 162 doctors were more than 59 years old, 162 doctors (7,9%) were died and 41,4% was general practitioner. The odds ratio in each risk factor for mortality was older age doctors 15,468 (95% CI 10,587-22,601), male 6,128 (95% CI 3,906-9,614), general practitioner 2,461 (95% CI 1,769-3,423), doctors with underlying disease 39,842 (95% CI 23,077-68,798), Type II diabetes mellitus 82,504 (95% CI 42,767-159,162), cardiovascular disease 50,152 (95% CI 16,672-150,866), hypertension 19,425 (95% CI 10,528-35,840), Chronic Obstructive Pulmonary Disease 5,52 (95% CI 0,610-49,992), Asthma 2,091 (95% CI 0,626-6,986), Obesity 30.750 (95% CI 15,293-61,828) and Pregnant doctors 43.013 (95% CI 10.986-168.414) (p |