Validation of Cariogram in Caries Prediction in Women and Their Children 4 Years After Pregnancy – Longitudinal Study
| Autor: | Slava Sukara, Zeljka Kojic, Marija Obradovic, Natasa Knezevic, Valentina Veselinović, Olivera Dolić, Nataša Trtić |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Pediatrics
medicine.medical_specialty Longitudinal study Pregnancy business.industry Offspring 030503 health policy & services Health Policy Incidence (epidemiology) Public Health Environmental and Occupational Health Cariogram medicine.disease 03 medical and health sciences 0302 clinical medicine medicine Population study 030212 general & internal medicine 0305 other medical science business Risk assessment Early childhood caries |
| Zdroj: | Risk Management and Healthcare Policy. 13:549-557 |
| ISSN: | 1179-1594 |
| DOI: | 10.2147/rmhp.s243907 |
| Popis: | Background Cariogram®, an algorithm-based software model, for predicting caries risk has been used to assess the caries risk profile of many different groups. The aims of the study were to evaluate Cariogram caries risk assessment during pregnancy with DMFT/dmft incidence in mothers and their children 4 years after pregnancy and to check if there is an association between children's caries risk profiles using Cariogram and caries risk profiles (by Cariogram) of their mothers during pregnancy. Methods The study population consisted of 96 pregnant women (average age 27.4±7.2 years at baseline) who completed clinical baseline examination and salivary tests. The follow-up study was initiated 4 years later and the 80 pairs of mother and children (from that pregnancy) were re-examined using the same procedure at baseline. An individual caries risk profile and DMFT/dmft incidence were made for each woman and child. The prediction of the Cariogram was compared to the actual dental experience in 4 years. Sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) for two cut-offs were calculated to express the outcome. Results The results showed a strong association between the risk categories of pregnant women and their offspring as well as between caries development in offspring and the Cariogram risk categories of pregnant women. Sensitivity and PPV for new DMFT (ΔDMFT>0) 4 years after for women were high (>80%) for those participants assessed with 0-60% "chance to avoid caries", as well as diagnostic accuracy (74.00%). High specificity (91.00%), very high PPV (95.00%) and clinically useful values according to Youden's index (0.53) were obtained for moderate-risk and two lowest-risk groups for dmft in children. Conclusion Cariogram was valid in the authors' sample only and highly predictive in caries risk assessment in investigated children based on caries risk assessment of their mothers in pregnancy. |
| Databáze: | OpenAIRE |
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