First-in-class drug candidate (MPH-220) efficiently improves spastic gait disorders by selective inhibition of fast skeletal muscle myosin-2

Autor: Mate Gyimesi, Adam I. Horvath, Demeter Turos, Sharad Kumar Suthar, Mate Penzes, Louise Canon, Carlos Kikuti, Kathleen Ruppel, Darshan V. Trivedi, James A. Spudich, Anna Á. Rauscher, Mihaly Kovacs, Samuel Komoly, Anne M. Houdusse, Andras Malnasi-Csizmadia
Rok vydání: 2022
Předmět:
Zdroj: Biophysical Journal. 121:291a
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2021.11.1291
Databáze: OpenAIRE