N-Methylation of Nitrogen-Containing Heterocycles with Dimethyl Carbonate

Autor:	Samedy Ouk, Elisabeth Borredon, Sophie Thiébaud, Bernard Chabaud
Rok vydání:	2006
Předmět:	chemistry.chemical_compound Piperazine chemistry Reagent Morpholine Organic chemistry Reactivity (chemistry) General Medicine Pyrazole Dimethyl carbonate Pyrrole Catalysis
Zdroj:	ChemInform. 37
ISSN:	1522-2667 0931-7597
DOI:	10.1002/chin.200615049
Popis:	Reactivity of dimethyl carbonate, the environmentally friendly reagent, as methylating agent for nitrogen‐containing heterocyclic compounds has been studied. Reactions of imidazole, pyrazole, pyrrole, morpholine, and piperazine with dimethyl carbonate to afford N‐methylated products were reported. The reactions were carried out with neither catalyst nor solvent at a temperature range of 110–170°C under atmospheric pressure.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::06f9c0201a6717f8962ee8c0cb1b2b9c https://doi.org/10.1002/chin.200615049 Zobrazit plný text záznamu Plný text