Process Research and Scale-Up for a β-3 Adrenergic Receptor Agonist

Autor:	Devries Keith Michael, Frank J. Urban, Michael W. Snyder, Brian C. Vanderplas, Raggon Jeffrey W, Fox Darrell E
Rok vydání:	2004
Předmět:	Agonist Beta-3 adrenergic receptor Adrenergic receptor medicine.drug_class Stereochemistry Chemistry Organic Chemistry Alpha-1B adrenergic receptor Alpha-1A adrenergic receptor Beta-1 adrenergic receptor medicine Inverse agonist Physical and Theoretical Chemistry Alpha-1D adrenergic receptor
Zdroj:	Organic Process Research & Development. 8:583-586
ISSN:	1520-586X 1083-6160
DOI:	10.1021/op049969o
Popis:	A scaleable synthesis of the β-3 adrenergic receptor agonist, (4-{2-[2-(6-aminopyridin-3-yl)-(2R)-hydroxy-ethylamino]ethoxy}phenyl)acetic acid is presented. The key coupling step utilizes a silyl-p...
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::06f9a3a675b0283cd924875d53aea249 https://doi.org/10.1021/op049969o Zobrazit plný text záznamu