Sixteen-and-a-half syndrome with metastatic pons tumor
| Autor: | Shin-Myeong Choi, Sang Woong Moon, Tae Gi Kim, In-Ki Park, Jae-Ho Shin, Jin-Ho Joo, Junkyu Chung |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Diplopia
medicine.medical_specialty Palsy business.industry Internuclear ophthalmoplegia Brain tumor Horizontal gaze palsy General Medicine medicine.disease Metastasis 03 medical and health sciences 0302 clinical medicine 030220 oncology & carcinogenesis Medicine 030212 general & internal medicine Radiology medicine.symptom business Lung cancer Brain metastasis |
| Zdroj: | Medicine. 98:e18006 |
| ISSN: | 1536-5964 0025-7974 |
| Popis: | Rationale One-and-a-half syndrome (OAAH) is characterized as the combination of ipsilateral horizontal gaze palsy and internuclear ophthalmoplegia. OAAH syndrome accompanied with 7th and 8th cranial nerve palsy is called 16-and-a-half syndrome. We aimed to report the case of 16-and-a-half syndrome with metastatic pons tumor. Patient concerns A 57-year-old male diagnosed with nonsmall-cell lung cancer (NSCLC) with brain metastasis occurring 15 months ago was referred to our clinic with the chief complaint of horizontal diplopia and right gaze palsy. Diagnosis According to the patient symptom, ocular examination, and radiographic findings, he was diagnosed as 16-and-a-half syndrome which was caused by brain tumor metastasis from NSCLC. Interventions We referred him to hemato-oncology department and he was treated with radiation and supportive therapy. Outcomes Unfortunately, the patient passed away 1 month later without improvement of ophthalmoplegia. Lessons The clinical findings of our case indicate 16-and-a-half syndrome caused by brain tumor metastasis from NSCLC, which to our knowledge has not been previously reported. The case highlights a rare cause of OAAH spectrum disease and the importance of a systemic work-up including associated neurologic symptoms and brain imaging in patients with horizontal gaze palsy. |
| Databáze: | OpenAIRE |
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