Obstructive Gastroparesis: Patient Selection and Effect of Laparoscopic Pyloroplasty

Autor: Jennifer Wellington, Paula S. Stuart, Kenneth L. Koch, Carl J. Westcott
Rok vydání: 2019
Předmět:
Zdroj: Journal of Gastrointestinal Surgery. 24:1778-1784
ISSN: 1873-4626
1091-255X
DOI: 10.1007/s11605-019-04240-x
Popis: Functional obstructive gastroparesis is an understudied subtype of gastroparesis with normal 3 cycle per minute gastric myoelectrical activity that responds to botulinum toxin A injection and balloon dilation of the pylorus. To determine the effect of pyloroplasty on symptoms, weight, gastric emptying, and gastric myoelectrical activity in patients with gastroparesis and normal 3 cycle per minute gastric myoelectrical activity. Ten patients (average age 36 years with gastroparesis and normal 3 cycle per minute gastric myoelectrical activity) who had at least two successful endoscopic pyloric therapies and then underwent pyloroplasty were identified. Electrogastrography with water load satiety test was performed to determine gastric myoelectrical activity. Gastric emptying was measured with 4-h scintigraphy. Six months after pyloroplasty, nine of ten patients reported improved symptoms and weight increased an average of 6.4 lb (p = 0.04). The average percentage of meal retained at 4 h decreased from 47% before to 16% after pyloroplasty (p
Databáze: OpenAIRE