Effect of Testosterone Propionate on Losses Incident to Inadequate Dietary Intake12
| Autor: | J. E. Appleton, E.A. MacLachlan, Nathan B. Talbot, Allan M. Butler, M. A. Linton |
|---|---|
| Rok vydání: | 1945 |
| Předmět: |
Muscle tissue
Testosterone propionate Diminution medicine.medical_specialty Endocrinology Diabetes and Metabolism Potassium Biochemistry (medical) Clinical Biochemistry chemistry.chemical_element Testosterone (patch) Creatine Biochemistry Excretion chemistry.chemical_compound Endocrinology medicine.anatomical_structure chemistry Weight loss Internal medicine medicine medicine.symptom |
| Zdroj: | The Journal of Clinical Endocrinology & Metabolism. 5:327-336 |
| ISSN: | 1945-7197 0021-972X |
| DOI: | 10.1210/jcem-5-8-327 |
| Popis: | IT is KNOWN that the ratio of potassium to nitrogen lost from the body during short periods of starvation with or without marked dehydration may exceed the ratio of potassium to nitrogen in normal muscle tissue (5, 6, 10, 12, 13, 16, 32). It has also been observed that the administration of testosterone to subjects receiving an adequate diet may at first lead to a ratio of potassium to nitrogen retained in the body greater than that which pertains in normal muscle tissue (28, 29). In such subjects the serum potassium may fall to extremely low levels (7, 28, 29). The administration of testosterone to an obese man during a period of submaintenance diet and weight loss resulted in a diminution in the urinary nitrogen output and an increase in the urinary excretion of organic acids (23). This observation suggests that testosterone diminishes the rate of utilization of protein or muscle tissue and necessitates an increase in the oxidation of fat to meet the energy requirements. |
| Databáze: | OpenAIRE |
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