Structure of Hydrogels and Activity of Proteins Immobilized in Them

Autor: Valuev Lev I, L. V. Vanchugova, M. Yu. Gorshkova, N. A. Sivov, I. L. Valuev
Rok vydání: 2021
Předmět:
Zdroj: Polymer Science, Series B. 63:404-407
ISSN: 1555-6123
1560-0904
DOI: 10.1134/s1560090421040114
Popis: The effect of the chemical structure of crosslinking agents on the activity of proteins in hydrogels obtained by the copolymerization of acrylamide, a crosslinking agent, and an unsaturated protein derivative is studied. It is shown that interaction between units of the hydrophobic crosslinking agent which increases with an increase in the length of the aliphatic region between the double bonds of the crosslinking agent leads to an additional “hydrophobic crosslinking” of macromolecules and causes a decrease in the activity of the immobilized protein.
Databáze: OpenAIRE