Chronic Pulmonary Coccidioidomycosis
| Autor: | George A. Sarosi, Fred E. Tosh, Irene L. Doto, James D. Parker |
|---|---|
| Rok vydání: | 1970 |
| Předmět: |
Pathology
medicine.medical_specialty Tuberculosis biology medicine.drug_class business.industry Coccidioides immitis Antibiotics General Medicine medicine.disease biology.organism_classification Gastroenterology Histoplasmosis Coccidioidin Internal medicine Amphotericin B medicine Sputum Coccidioides medicine.symptom business medicine.drug |
| Zdroj: | New England Journal of Medicine. 283:325-329 |
| ISSN: | 1533-4406 0028-4793 |
| DOI: | 10.1056/nejm197008132830701 |
| Popis: | Of 109 patients with proved coccidioidomycosis 20 had chest films and clinical findings indistinguishable from either chronic pulmonary histoplasmosis or chronic pulmonary tuberculosis. Many were thought to have tuberculosis for years before the fungal etiology of the lung disease was determined. Coccidioides immitis was cultured from sputums of 18 of 19 patients, and coccidioidin complement-fixation tests were positive in 14 of 15. Best therapeutic results were obtained with amphotericin B intravenously in a total dose of 30 mg per kilogram of body weight or more. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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