Effect of Neurosurgical Operations on the Neurohypophyseal Function

Autor: Hideaki Iwasa, Toshikazu Saitoh, Fumiaki Satoh
Rok vydání: 1981
Předmět:
Zdroj: Neurologia medico-chirurgica. 21:583-589
ISSN: 1349-8029
0470-8105
DOI: 10.2176/nmc.21.583
Popis: Following neurosurgical operations, diabetes insipidus or SIADH is often observed, the former characterized b) polyuria, hypernatremia and a low plasma level of arginine vasopressin (AVP) ; and the latter by hyponatremie and a high plasma level of AVP. In this study, plasma levels of AVP, human growth hormone (HGH), nicotine stimulated neurophysine (NSN), estrogen stimulated neurophysine (ESN), sodium and creatinine; plasma osmolarity and urine output were measured during neurosurgical operations. Plasma levels of AVP, NSN, ES? and HGH were assayed by radio-immunoassay. Plasma AVP and NSN rose to the highest level towards the end of each operation in parallel with the change of plasma HGH levels. Significant correlation was observed betweerr the plasma levels of AVP [y: (pg/ml)] and NSN [x: (ng/ml)]; y=2.lx+6.5 (r=0.64, P
Databáze: OpenAIRE