Effect of Neurosurgical Operations on the Neurohypophyseal Function
Autor: | Hideaki Iwasa, Toshikazu Saitoh, Fumiaki Satoh |
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Rok vydání: | 1981 |
Předmět: |
endocrine system
Creatinine medicine.medical_specialty Vasopressin Surgical stress Arginine urogenital system medicine.drug_class business.industry medicine.disease chemistry.chemical_compound Endocrinology nervous system chemistry Polyuria Estrogen Internal medicine Diabetes insipidus medicine Surgery Neurology (clinical) Hypernatremia medicine.symptom business hormones hormone substitutes and hormone antagonists |
Zdroj: | Neurologia medico-chirurgica. 21:583-589 |
ISSN: | 1349-8029 0470-8105 |
DOI: | 10.2176/nmc.21.583 |
Popis: | Following neurosurgical operations, diabetes insipidus or SIADH is often observed, the former characterized b) polyuria, hypernatremia and a low plasma level of arginine vasopressin (AVP) ; and the latter by hyponatremie and a high plasma level of AVP. In this study, plasma levels of AVP, human growth hormone (HGH), nicotine stimulated neurophysine (NSN), estrogen stimulated neurophysine (ESN), sodium and creatinine; plasma osmolarity and urine output were measured during neurosurgical operations. Plasma levels of AVP, NSN, ES? and HGH were assayed by radio-immunoassay. Plasma AVP and NSN rose to the highest level towards the end of each operation in parallel with the change of plasma HGH levels. Significant correlation was observed betweerr the plasma levels of AVP [y: (pg/ml)] and NSN [x: (ng/ml)]; y=2.lx+6.5 (r=0.64, P |
Databáze: | OpenAIRE |
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