Evaluation of the aqueous extract ofRotula aquaticaroots in acute and chronic inflammatory conditions in rats

Autor: S.A. Mengi, V.J. Bakshi
Rok vydání: 2009
Předmět:
Zdroj: Pharmaceutical Biology. 47:491-495
ISSN: 1744-5116
1388-0209
DOI: 10.1080/13880200902835705
Popis: The aqueous extract of Rotula aquatica Lour (Boraginaceae) roots was investigated for its anti-inflammatory potential in acute and chronic inflammatory conditions in rats. The aqueous extract of the plant at doses 50, 100, and 200 mg kg−1, p.o., were screened against carrageenan-induced rat paw edema, cotton pellet-induced granuloma as well as crystal-induced inflammation in rats. The IL-6 levels in the exudates formed due to crystal-induced inflammation were also determined. The extract exhibited a statistically significant (p
Databáze: OpenAIRE
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