The Biological Activity of Di- -Tocopherone
| Autor: | A. Saari Csallany, J. G. Bergan, H.H. Draper, D. J. Lee |
|---|---|
| Rok vydání: | 1963 |
| Předmět: |
medicine.medical_specialty
Vitamin E medicine.medical_treatment Metabolite Biological activity Metabolism Biology medicine.disease Congenital myopathy General Biochemistry Genetics and Molecular Biology chemistry.chemical_compound Endocrinology chemistry Internal medicine medicine Nutritional muscular dystrophy Muscular dystrophy alpha-Tocopherol |
| Zdroj: | Experimental Biology and Medicine. 113:242-245 |
| ISSN: | 1535-3699 1535-3702 |
| DOI: | 10.3181/00379727-113-28330 |
| Popis: | SummaryDi-α-tocopherone, a recently characterized metabolite of α-tocopherol isolated from animal tissues, was tested for biological activity with respect to resorption-gestation in Vit. E-deficient rats, nutritional muscular dystrophy in rabbits and hereditary muscular dystrophy in mice. The results indicate that this metabolite has less than 5% of the Vit. E activity of α-tocopherol and that it possesses no therapeutic value in treatment of the congenital myopathy. Its probable role in metabolism is that of a terminal oxidation product rather than an active form of Vit. E. |
| Databáze: | OpenAIRE |
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