Optic perineuritis with anti-myelin oligodendrocyte glycoprotein antibody
Autor: | Hirofumi Emoto, Takanori Yokota, Takaaki Hattori, Mitsugu Yanagidaira, Motohiro Kiyosawa |
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Rok vydání: | 2020 |
Předmět: |
Pathology
medicine.medical_specialty genetic structures Fundus (eye) Myelin oligodendrocyte glycoprotein 03 medical and health sciences 0302 clinical medicine Cerebrospinal fluid medicine 030212 general & internal medicine chemistry.chemical_classification biology business.industry Multiple sclerosis General Medicine medicine.disease eye diseases Oligodendrocyte medicine.anatomical_structure Neurology chemistry biology.protein Optic nerve sense organs Neurology (clinical) Antibody Glycoprotein business 030217 neurology & neurosurgery |
Zdroj: | Multiple Sclerosis and Related Disorders. 38:101444 |
ISSN: | 2211-0348 |
DOI: | 10.1016/j.msard.2019.101444 |
Popis: | A 25-year-old male presented with blurred peripheral vision and movement pain in his right eye. Fundus examination revealed unilateral disc swelling in his right eye with normal intracranial pressure. MRI showed remarkably high intensity in the optic nerve sheath and slightly high intensity in the optic nerve, indicating optic perineuritis (OPN). Anti-myelin oligodendrocyte glycoprotein (MOG) antibody was positive in both serum and cerebrospinal fluid. The patient responded promptly to corticosteroid treatment. OPN can be associated with the presence of anti-MOG antibody. |
Databáze: | OpenAIRE |
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