Progestin Content of Human Placenta

Autor: J. G. Wolter, D. A. McGinty, N. B. McCullough
Rok vydání: 1936
Předmět:
Zdroj: Experimental Biology and Medicine. 34:176-178
ISSN: 1535-3699
1535-3702
DOI: 10.3181/00379727-34-8547c
Popis: The amount of progestational hormone in the human placenta is of interest not only because of contradictory reports as to the quantity present but because of the significance of this organ along with the corpus luteum as a source of luteal hormone during pregnancy.Ehrhardt and Weigel1 using implantation methods reported failure to demonstrate corpus luteum hormone in the human placenta. However, Ehrhardt2 a few months later, using at this time placental extracts from which estrogenic fractions were separated, found as much as 10 (Clauberg) rabbit units in a single term placenta. Negative or weakly positive results were obtained in every instance when unseparated extracts were injected.Adler, Fremery and Tausk3 likewise demonstrated the presence of hormone in human placentas but only when estrogenic substances were removed. They reported, however, one rabbit unit in 500 to 1500 gm. fresh tissue or roughly one rabbit (Corner-Allen) unit per placenta.Using the method of Corner and Allen for preparation of to...
Databáze: OpenAIRE