Progestin Content of Human Placenta
Autor: | J. G. Wolter, D. A. McGinty, N. B. McCullough |
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Rok vydání: | 1936 |
Předmět: |
medicine.medical_specialty
Weakly positive medicine.drug_class ESTROGENIC SUBSTANCES Human placenta Biology General Biochemistry Genetics and Molecular Biology Luteal hormone Endocrinology medicine.anatomical_structure Internal medicine medicine Placental Extracts Progestin Corpus luteum reproductive and urinary physiology Hormone |
Zdroj: | Experimental Biology and Medicine. 34:176-178 |
ISSN: | 1535-3699 1535-3702 |
DOI: | 10.3181/00379727-34-8547c |
Popis: | The amount of progestational hormone in the human placenta is of interest not only because of contradictory reports as to the quantity present but because of the significance of this organ along with the corpus luteum as a source of luteal hormone during pregnancy.Ehrhardt and Weigel1 using implantation methods reported failure to demonstrate corpus luteum hormone in the human placenta. However, Ehrhardt2 a few months later, using at this time placental extracts from which estrogenic fractions were separated, found as much as 10 (Clauberg) rabbit units in a single term placenta. Negative or weakly positive results were obtained in every instance when unseparated extracts were injected.Adler, Fremery and Tausk3 likewise demonstrated the presence of hormone in human placentas but only when estrogenic substances were removed. They reported, however, one rabbit unit in 500 to 1500 gm. fresh tissue or roughly one rabbit (Corner-Allen) unit per placenta.Using the method of Corner and Allen for preparation of to... |
Databáze: | OpenAIRE |
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