Hybrid cells, infected with Theileria parva, formed by fusion of hamster and mouse cells with parasitised bovine lymphoid cells

Autor:	A.D. Irvin, L.W. Rowe, C.G.D. Brown, G.K. Kanhai, D.A. Stagg
Rok vydání:	1975
Předmět:	Heterokaryon General Veterinary biology viruses Theileria parva Hamster Anatomy biology.organism_classification Molecular biology Sendai virus parasitic diseases Baby hamster kidney cell Parasite hosting Mouse Heart
Zdroj:	Research in Veterinary Science. 19:142-151
ISSN:	0034-5288
DOI:	10.1016/s0034-5288(18)33524-0
Popis:	Bovine lymphoid cells from a culture line parasitised with Theileria parva were fused to mouse heart (MH) and baby hamster kidney (BHK) cells, grown as monolayers, using inactivated Sendai virus. The resultant heterokaryons contained macroschizonts of T parva. Macroschizonts also occurred in cells that apparently contained only BHK or MH nuclei. Parasites underwent varying degrees of development; in some cases microschizonts resulted, and in other cases massive atypical parasite masses were formed. Fusion occurred more readily between hamster and bovine cells than between mouse and bovine cells.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::060b54c471b2ba7e801f5f8550ff785b https://doi.org/10.1016/s0034-5288(18)33524-0 Zobrazit plný text záznamu