A New Nonglycosidic Iridoid from Aerial Parts of Gelsemium elegans
| Autor: | Dongmei Wang, Zhimin Zhao, Qin Liu, Juan Shen, Long-Ping Zhu, Shi-Yi Peng, Depo Yang, Bai Bai |
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| Rok vydání: | 2019 |
| Předmět: |
Gelsemium elegans
Iridoid 010405 organic chemistry Chemistry medicine.drug_class Plant Science General Chemistry Aqueous ethanol 01 natural sciences General Biochemistry Genetics and Molecular Biology 0104 chemical sciences 010404 medicinal & biomolecular chemistry medicine Organic chemistry No release |
| Zdroj: | Chemistry of Natural Compounds. 55:275-277 |
| ISSN: | 1573-8388 0009-3130 |
| DOI: | 10.1007/s10600-019-02665-z |
| Popis: | A new nonglycosidic iridoid, geleganoid G (1), together with six previously reported analogues (2–7), were isolated from the aqueous ethanol extract of the aerial parts of Gelsemium elegans. Their structures were elucidated on the basis of extensive spectroscopic analyses and comparison with data from the literature. It is proved that 1 is a new compound by using LC-ESI-MS. All compounds were evaluated for inhibition of LPS-induced NO release in RAW 264.7 cells in vitro. Only compound 3 displayed moderate inhibition of NO release. |
| Databáze: | OpenAIRE |
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