9-pyridylidenefluorenes, a new class of anti-inflammatory substances

Autor:	P. Jacquignon, M. P. Sinh, J. F. Sabathier, N. P. Buu-Hoï, A. Rose, Delbarre F, Brouilhet H
Rok vydání:	2010
Předmět:	Oral dose chemistry.chemical_compound medicine.drug_class Prednisone Chemistry medicine General Chemistry Fluorene Pharmacology Anti-inflammatory medicine.drug
Zdroj:	Recueil des Travaux Chimiques des Pays-Bas. 82:1047-1050
ISSN:	0165-0513
DOI:	10.1002/recl.19630821102
Popis:	The condensation of fluorene with the three formylpyridines and 2-formyl-6-methylpyridine has been investigated, and the 9-pyridylidenefluorenes obtained have been tested in rats for anti-inflammatory activity. 9-(3-Pyridylidene)fluorene proved the most potent compound, with an activity half of that of subcutaneously injected prednisone, in an oral dose ten times greater.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::05bc4be87d741df985ce817617e19e95 https://doi.org/10.1002/recl.19630821102 Zobrazit plný text záznamu