Stimulated Hofbauer Cells in the Placental Villi from Patients with Second-Trimester Abortions
| Autor: | Akio Izumi, Takuma Saito, Ikuo Sato, Toshihiro Takizawa, Tetsuo Yamada, Toshimitsu Koike, Shigeki Matsubara, Hisanori Minakami |
|---|---|
| Rok vydání: | 1998 |
| Předmět: |
Histology
Physiology Acid phosphatase Cell Biology Biology Biochemistry Pathophysiology Pathology and Forensic Medicine Andrology medicine.anatomical_structure Second trimester Cytoplasm Placenta embryonic structures Immunology biology.protein medicine Gestation Normal control reproductive and urinary physiology Phagosome |
| Zdroj: | ACTA HISTOCHEMICA ET CYTOCHEMICA. 31:447-452 |
| ISSN: | 1347-5800 0044-5991 |
| DOI: | 10.1267/ahc.31.447 |
| Popis: | The purpose of this study was to characterize the ultrastructural and enzyme-histochemical features of Hofbauer cells in the placental villi of second-trimester abortions. Hofbauer cells in the abortive placenta had more numerous cytoplasmic processes and more prominent phagosomes as compared to gestational age-matched normal control placenta. Acid phosphatase activity was demonstrated in both the lysosomes and on phagosomal membranes of these cells. Our results indicate that Hofbauer cells in second-trimester abortions are activated or stimulated in situ. These activated Hofbauer cells might play important roles in the pathophysiology of preterm parturition. |
| Databáze: | OpenAIRE |
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